ConclusionsPsychosomatic disorders in GERD have a significant impact not only on the quality of sleep, quality of life, the level of melatonin and serotonin, the regulation of the secretory and motor functions of the stomach, but they are one of the links in the pathogenetic mechanism of the formation of both GERD and insomnia with it.The aim To study the prevalence of ABR among children with UTI over the past 10 years, with an assessment of the sensitivity of E. Coli to common antibiotics in dynamics.
Materials and methods The study involved 1,044 children with UTI aged from 1 month to 18 years. Examination of patients and interpretation of the results was performed in accordance with the provisions of the Declaration of Helsinki of Human Rights. According to the design, the study included 3 comparison groups Group 1 - children of the 2009 follow-up year (n = 337), Group 2 - of 2014 (n = 328) and Group 3 - of 2019 (n = 379).
Results Escherichia coli is recognized as the leading uropathogen in all study groups its percentage in Group 1 was 47 % (158/337), in Group 2 - 64 % (210/328) and in Group 3 - 66.5 % (252/379). The prevalence of antibacterial resistance of E. coli strains and the high dynamics of its growth are shown. So the level of resistance of E. https://www.selleckchem.com/products/bay-3827.html Coli in 2019 was 70 ± 4.06 % (176/252). This was 11 % more compared to 2014 anion. An unfavourable prognosis of an increase in the relative risk of ABR by 2.9-3.7 times in the next 5-10 years was determined among patients with UTI, provided that the existing diagnostic and treatment approaches are maintained.
Conclusions The study results are important for understanding the clinical decision on the benefits of antibacterial therapy and optimizing its empirical choice for a patient with UTI.
Conclusions The study results are important for understanding the clinical decision on the benefits of antibacterial therapy and optimizing its empirical choice for a patient with UTI.The aim To investigate the informative content of immunocytochemical studies of lymph node aspirate using a molecular marker of cytokeratin 19 in patients with laryngeal cancer as for regional metastastatic spread.
Materials and methods A comprehensive investigation with immunohistochemical study of squamous cell carcinoma of larynx of 74 patients with laryngeal cancer II - IV stage (T2-4 N0-3 M0) of the second clinical group was conducted.
Results Statistically significant differences (p &lt;0.001) in the structure of distribution of marker expression between groups were revealed. Thus, a marked expression of cytokeratin 19 was determined in 11 (29.73%) representatives of the group with regional metastases and only in 1 (2.7%) patient without tumor metastases (p = 0.002). In the group with metastases the presence of atypical cells was confirmed cytologically in 26 cases (70,27%).
Conclusions To predict the development of laryngeal metastases in laryngeal cancer patients, it is recommended to carry out an immunocytochemical study using a diagnostic marker of cytokeratin 19. The positive status of cytokeratin 19 increases the chances of regional metastasis of laryngeal cancer by 18.37 times (p&lt;0.001) compared with absence of expression.
Conclusions To predict the development of laryngeal metastases in laryngeal cancer patients, it is recommended to carry out an immunocytochemical study using a diagnostic marker of cytokeratin 19. The positive status of cytokeratin 19 increases the chances of regional metastasis of laryngeal cancer by 18.37 times (p less then 0.001) compared with absence of expression.The aim was the evaluation the patient's quality of life with muscular and joint dysfunction of TMJ with using a modified profile questionnaire at various stages of orthopedic treatment. The study was conducted at the Department of Orthopedic Dentistry on the base of University Dental Center in Kharkiv National Medical University.
Materials and methods Weconductedaclinicalexamination andsubjectiveanalysisof 125 patientsaged 20 to 60 years (mean age 38.5 ± 3), and 80 of themwith areliable diagnosisofdysfunction ofTMJ andacontrolgroupof 45 patientsof thesameage withoutpathologyofTMJ. Our profile questionnaire is intended for filling by the respondent (patient) at the three control stages of orthopedic treatment under the supervision of an orthopedic dentist (before the start of treatment, 1.5 months after the beginning of treatment and 3 months). The data obtained were subjected to a scaling process, converted into percentages to facilitate statistical analysis.
ResultsThe worst values before and after trnaire can be used to evaluate the dynamics of orthopedic treatment of this complex pathology, and it can also be used as a prognostic criterion for the end of the disease.The aim To study possibilities of prognosis of pathological wear of tooth hard tissues development depending on the functional activity of masticatory muscles.
Materials and methods In order to achieve the goal of the study, a survey of patients at the age of 19 to 69 years was conducted for precision of number of persons who have increased tooth wear. During the examination of all patients, three groups were selected control and two researched ones. Patients in the control group (30 patients between the age of 18 and 60 years old) had an intact dentition without any visible sign of increased tooth wear. The researched groups included 25 patients aged from 18 to 60 years old. The secondresearch group included patients who had increased tooth wear of I-III level. The children of the patients of the II group with or without any sign of increased tooth wear were referred to the third research group.
Results The method of electromyography was performed for the study of peculiarities of the muscular activity of the maxillofacial area of the patients of the control and research groups. In our opinion, all manifestations of increased tooth wear are related to changes in the muscle system, the motor apparatus and the nervous activity of an organism.
Conclusions The study of direct muscular apparatus and related bone system may predict the possibility of developing of an increased tooth wear of young patients in the future and prevent its development, as well as to justify the application of a prevention and treatment plan of the studied pathology.
Conclusions The study of direct muscular apparatus and related bone system may predict the possibility of developing of an increased tooth wear of young patients in the future and prevent its development, as well as to justify the application of a prevention and treatment plan of the studied pathology.